Glenn F King Selected Research

Spider Venoms (Venom, Spider)

1/2021	A spider-venom peptide with multitarget activity on sodium and calcium channels alleviates chronic visceral pain in a model of irritable bowel syndrome.
1/2019	The modulation of acid-sensing ion channel 1 by PcTx1 is pH-, subtype- and species-dependent: Importance of interactions at the channel subunit interface and potential for engineering selective analogues.
1/2017	Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi.
1/2017	Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a.
12/2016	Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7.
1/2016	Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain.
10/2014	Spider venomics: implications for drug discovery.
12/2010	Spider-venom peptides as therapeutics.

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Glenn F King Research Topics

Disease

31	Pain (Aches) 01/2022 - 03/2012
11	Paralysis (Palsy) 12/2020 - 02/2006
9	Chronic Pain 01/2021 - 12/2010
6	Neoplasms (Cancer) 01/2021 - 03/2012
5	Hypersensitivity (Allergy) 01/2022 - 01/2014
5	Bites and Stings (Sting) 10/2021 - 01/2012
4	Epilepsy (Aura) 11/2020 - 01/2015
4	Ischemic Stroke 01/2019 - 11/2011
3	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 08/2021 - 01/2018
3	Stroke (Strokes) 01/2017 - 10/2014
3	Inflammation (Inflammations) 05/2014 - 12/2010
2	Melanoma (Melanoma, Malignant) 10/2022 - 01/2018
2	Visceral Pain 08/2021 - 01/2021
2	Multiple Sclerosis 01/2021 - 01/2012
2	Rheumatoid Arthritis 10/2020 - 01/2012
2	Acidosis 01/2019 - 01/2017
2	Acute Pain 01/2019 - 11/2011
2	Brain Ischemia (Cerebral Ischemia) 01/2017 - 12/2015
2	Congenital Pain Insensitivity 10/2013 - 03/2012
1	Foreign Bodies (Foreign Body) 10/2021
1	Nociceptive Pain 08/2021
1	HIV Infections (HIV Infection) 01/2021
1	Reperfusion Injury 01/2021
1	Body Weight (Weight, Body) 01/2021
1	Osteoporosis 01/2021
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2021
1	Acquired Immunodeficiency Syndrome (AIDS) 11/2020
1	Parasitic Diseases (Parasitic Disease) 11/2020
1	Graft vs Host Disease (Graft-Versus-Host Disease) 10/2020
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2020
1	Wounds and Injuries (Trauma) 03/2020
1	Leishmaniasis 06/2019
1	Trypanosomiasis 06/2019
1	Neurogenic Inflammation 01/2019
1	Necrosis 12/2018
1	Shellfish Poisoning 10/2018
1	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2018
1	Seizures (Absence Seizure) 01/2018
1	Hypertension (High Blood Pressure) 01/2018
1	Drug Resistant Epilepsy 01/2018

Drug/Important Bio-Agent (IBA)

22	VenomsIBA 01/2022 - 01/2012
20	Peptides (Polypeptides)IBA 10/2022 - 08/2007
12	Analgesics (Analgesic Drugs)IBA 01/2018 - 11/2011
10	Voltage-Gated Sodium ChannelsIBA 08/2021 - 03/2012
8	Spider Venoms (Venom, Spider)IBA 01/2021 - 12/2010
7	SodiumIBA 01/2022 - 01/2016
7	Acid Sensing Ion ChannelsIBA 01/2021 - 07/2012
7	Ion Channels (Ion Channel)IBA 11/2020 - 01/2012
5	Proteins (Proteins, Gene)FDA Link 12/2020 - 01/2012
4	AcidsIBA 01/2019 - 10/2013
4	Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)IBA 12/2018 - 01/2012
2	Ant VenomsIBA 01/2022 - 10/2021
2	Tetrodotoxin (Tetradotoxin)IBA 01/2022 - 10/2018
2	CalciumIBA 01/2021 - 11/2019
2	Calcium Channels (Calcium Channel)IBA 01/2021 - 02/2006
2	Pharmaceutical PreparationsIBA 10/2020 - 01/2018
2	DiminazeneIBA 06/2019 - 01/2018
2	Scorpion Venoms (Scorpion Venom)IBA 01/2019 - 08/2015
2	Morphine (MS Contin)FDA LinkGeneric 01/2018 - 10/2013
2	DisulfidesIBA 01/2017 - 12/2016
2	NeurotoxinsIBA 01/2014 - 08/2013
1	TachykininsIBA 10/2022
1	Adenosine Triphosphate (ATP)IBA 10/2022
1	Epidermal Growth Factor (EGF)IBA 01/2022
1	ErbB Receptors (EGF Receptor)IBA 01/2022
1	Hormones (Hormone)IBA 01/2022
1	Monophenol Monooxygenase (Tyrosinase)IBA 10/2021
1	GlycopeptidesIBA 10/2021
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2021
1	FatsIBA 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 01/2021
1	Antineoplastic Agents (Antineoplastics)IBA 01/2021
1	CecropinsIBA 01/2021
1	Insulin (Novolin)FDA Link 01/2021
1	margatoxinIBA 01/2021
1	Cysteine Loop Ligand-Gated Ion Channel ReceptorsIBA 11/2020
1	Neurotransmitter Agents (Neurotransmitter)IBA 11/2020
1	Biological ProductsIBA 11/2020
1	Ionotropic Glutamate ReceptorsIBA 11/2020
1	SolutionsIBA 03/2020
1	Peptide Hydrolases (Proteases)FDA Link 03/2020
1	Pentamidine (NebuPent)FDA LinkGeneric 06/2019
1	NeuropeptidesIBA 01/2019
1	Protons (Proton)IBA 01/2019
1	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2018
1	Ether (Diethyl Ether)IBA 12/2018
1	7- O- (2,6- dideoxy- 2- fluorotalopyranosyl)daunomycinoneIBA 12/2018
1	SaxitoxinIBA 10/2018
1	Cystine-Knot MiniproteinsIBA 10/2018
1	Phosphotransferases (Kinase)IBA 01/2018
1	Acid Sensing Ion Channel BlockersIBA 01/2018
1	gomesinIBA 01/2018

Therapy/Procedure

6	Therapeutics 10/2022 - 12/2010
2	Analgesia 01/2022 - 08/2021
1	Immunotherapy 10/2022
1	Drug Therapy (Chemotherapy) 01/2021
1	Aftercare (After-Treatment) 01/2021
1	Ligation 10/2018
1	Intraventricular Infusions 01/2018
1	Precision Medicine 01/2018